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2025’s Top Rehab Centers in Greenville, 6 (Free) Drug & Alcohol Support Resources
Greenville, South Carolina

Compare costs, reviews, insurance, amenities, and treatments for 8 inpatient, 31 outpatient, and 7 detox centers to find the best drug and alcohol rehab center for you in and near Greenville, SC. Filter for 2025's top accredited, free, and luxury addiction treatment programs. If you’re trying to find the best care for your needs in Greenville, you’ll also find long-term recovery housing and medications for addiction treatment (MAT). Pregnant people and those who use substances intravenously receive priority admission to detox centers. If you are on South Carolina Medicaid, you should be eligible for rehab coverage. Most private insurance plans are accepted, and if you don’t have insurance, there are free or very low-cost programs available. If you are looking for specialized or luxury residential programs — or residential care for adolescent girls — you’ll likely need to look beyond Greenville. Learn more about how to choose the best treatment option.
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  • BriteLife Recovery at Hilton Head

    Hilton Head Island, SC

    (200)
    Located on a private, tree-lined property, BriteLife Recovery South Carolina is a luxury rehab offering detox and residential treatment for substance use and co-occurring mental health disorders in Hilton Head. The center combines evidence-based and trauma-informed care with holistic therapies such as mindfulness, art, and equine therapy. Gender-specific tracks, private or semi-private rooms, chef-prepared meals, and resort-style amenities like a pool and beach access, create a serene coastal environment that supports comfort, healing, and long-term recovery.
    • Available Services Recovery support services Treats alcohol use disorder Treats opioid use disorder Mental health treatment
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • 1Accreditation(s)
    • Accepting Clients
  • (8)
    301 Augusta St Unit 101, Greenville, SC 29601 864-513-6337
    Lantana Recovery Greenville, South Carolina connects people in Upstate South Carolina to flexible addiction and dual diagnosis treatment. Services include medications for addiction treatment (MAT), trauma-informed therapy, sober living, and family support. With transportation, telehealth, and payment plan options, the program reduces barriers for those balancing recovery with family needs.
    • Available Services Treats alcohol use disorder Treats opioid use disorder Mental health treatment
    • Detox For Opioids Alcohol Benzodiazepines Cocaine Methamphetamines
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • 1Accreditation(s)
    • Medication
    • Accepting Clients
  • (48)
    $
    602 Airport Road, Suite C, Greenville, SC 29607 844-733-6743
    Located near Greenville, South Carolina’s Downtown Airport, Greenville Metro Treatment Center is part of New Season, a nationwide treatment network providing comprehensive outpatient care designed to support opioid recovery. The center’s flexible programs allow clients to continue their daily activities while receiving care. Services include medications for addiction treatment (MAT), with options such as methadone, buprenorphine and Suboxone, to address withdrawal and cravings. Licensed counseling services are integrated into care plans and clients who reach certain milestones in their recovery can receive take-home medications. A mobile unit brings on-the-go counseling and medication services to clients living in remote areas.
    • Available Services Recovery support services Treats opioid use disorder
    • Detox For Opioids
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • 2Accreditation(s)
    • Medication
    • Accepting Clients
  • 520 Lowndes Hill Road, Greenville, SC 29607 888-819-4214 x701
    Solutions Recovery Center offers specialized services for clients with legal mandates, including support for court-ordered treatment compliance and veteran-focused court requirements. The center provides a range of treatments for substance use and co-occurring mental health disorders, with a focus on spiritual growth and holistic recovery. Gender-specific sober living, a comprehensive 12-Step video resource, and career-building programs add structure and support. Patient reviews highlight a compassionate staff and strong community environment, making it a solid choice for those committed to a spiritual recovery journey.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • Treatment Setting Inpatient
    • Insurance Accepted Blue Cross Blue Shield IHS
    • 1Accreditation(s)
  • (8)
    $
    6 Dunean Street, Greenville, SC 29611 864-467-3881
    Located near downtown Greenville, South Carolina, Serenity Place is a residential program where pregnant women and mothers of young children can recover from substance use disorder while living with their kids. Set in a home-like facility with on-site childcare and green space, the program provides trauma-informed therapy, parenting education, and medications for addiction treatment (MAT). With space for up to 16 women and their children, the program prioritizes those with urgent medical or recovery needs and offers a safe, family-centered path toward long-term stability.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female
    • 2Accreditation(s)
    • Medication
  • $
    130 Industrial Drive, Suite 130, Greenville, SC 29607 864-467-3770
    Phoenix Center - Detoxification Unit is located in Greenville, South Carolina. They provide payment assistance. They provide a sliding fee scale. They provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder
    • Detox For Opioids Alcohol Benzodiazepines
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • Treatment Setting Hospital Detox
    • Insurance Accepted Medicaid Private (Any)
    • 2Accreditation(s)
    • Medication
  • $
    1400 Cleveland Street, Greenville, SC 29607 864-467-3790
    Phoenix Center - Adult Outpatient Services is located in Greenville, South Carolina. They offer special programs for Service members, Adolescents, Adult men, Adult women, Court referrals, Military families, Past domestic violence, Past sexual abuse, Past trauma, Mental health disorders, HIV/AIDS, Pregnant/postpartum, Veterans, Pain management, Seniors and Young adults. They provide payment assistance. They provide a sliding fee scale. They provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder
    • Ages Youth (Ages 12-17)
    • Gender Female Male
    • Treatment Setting Outpatient Telemedicine
    • Insurance Accepted Medicaid Private (Any)
    • 2Accreditation(s)
    • Medication
  • $$$
    16 Mills Avenue, Suite 8, Greenville, SC 29605 864-775-5509
    Life Line Services LLC is located in Greenville, South Carolina. They offer special programs for Past trauma, Mental health disorders, Pregnant/postpartum and Pain management. They provide payment assistance. They do not provide a sliding fee scale. They provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder Mental health treatment
    • Detox For Opioids Alcohol Benzodiazepines Cocaine Methamphetamines
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • Treatment Setting Outpatient Telemedicine Detox
    • Insurance Accepted Private (Any)
    • 1Accreditation(s)
    • Medication
  • , Greenville, SC 29615 864-241-6688
    Pavillon - Greenville Outpatient Services is located in Greenville, South Carolina. They offer special programs for Mental health disorders and Pain management. They do not provide payment assistance. They do not provide a sliding fee scale. They provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder Mental health treatment
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • 1Accreditation(s)
    • Medication
  • $
    157 Brozzini Court, Suite C, Greenville, SC 29615 800-805-6989
    Crossroads Treatment Centers - Greenville PC is located in Greenville, South Carolina. They offer special programs for Pregnant/postpartum. They do not provide payment assistance. They do not provide a sliding fee scale. They provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats opioid use disorder
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • 3Accreditation(s)
    • Medication
  • 207 West Antrim Drive, Greenville, SC 29607 864-567-7010 x707
    Solutions Recovery Counseling is located in Greenville, South Carolina. They offer special programs for Service members, Adult men, Adult women, Court referrals, Military families, Past domestic violence, Past sexual abuse, Past trauma, Veterans, Seniors and Young adults. They do not provide payment assistance. They do not provide a sliding fee scale. They do not provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • Treatment Setting Outpatient
    • Insurance Accepted IHS
    • 1Accreditation(s)
  • 144 Faith Home Road, Greenwood, SC 29649 864-223-0694
    Faith Home Inc - Christian Alcohol/Drug Rehabilitation is located in Greenwood, South Carolina. They offer special programs for Adult men. They do not provide payment assistance. They do not provide a sliding fee scale. They do not provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Male
    • Treatment Setting Inpatient
    • Insurance Accepted Aetna Blue Cross Blue Shield Free
    • 1Accreditation(s)
  • $
    129 Dillon Drive, Spartanburg, SC 29307 864-582-7588
    Located in Spartanburg, South Carolina, Forrester Center for Behavioral Health provides outpatient treatment for substance use and co-occurring mental health disorders. This nonprofit offers medications for addiction treatment (MAT), counseling for adults and adolescents, and peer-supported recovery services. Its smoke-free campus features flexible scheduling with morning, evening, and weekend sessions. The center also provides community education and court-related programs, helping residents of Spartanburg County access affordable, person-centered care close to home.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder
    • Ages Youth (Ages 12-17)
    • Gender Female Male
    • Treatment Setting Inpatient Outpatient Telemedicine
    • Insurance Accepted Medicaid Private (Any) State
    • 5Accreditation(s)
    • Medication
  • , Cowpens, SC 29330 864-223-0694
    Faith Home Inc - Womens Facility is located in Cowpens, South Carolina. They offer special programs for Adult women. They do not provide payment assistance. They do not provide a sliding fee scale. They do not provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female
    • Treatment Setting Inpatient
    • Insurance Accepted Free
    • 1Accreditation(s)
  • (46)
    $$
    405 West Cherokee Street, Chesnee, SC 29323 877-323-4713
    Situated on two acres in a spacious, home-like environment, American Detox and Residential Treatment Center provides detox and residential care for adults. Amenities are ADA-accessible and feature private room options and an array of recreational activities. Clients participate in up to 27 hours of group therapy each week, including 12-step gatherings. Most staff members are in long-term recovery, providing dedicated peer mentorship and support. A specialized recovery track is available for veterans and first responders.
    • Available Services Luxury Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder Mental health treatment
    • Detox For Opioids Alcohol Benzodiazepines Cocaine Methamphetamines
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • 2Accreditation(s)
    • Medication
    • Luxury
  • , Abbeville, SC 29620 864-223-0694
    Faith Home Inc - Womens Facility is located in Abbeville, South Carolina. They offer special programs for Adult women. They do not provide payment assistance. They do not provide a sliding fee scale. They do not provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female
    • Treatment Setting Inpatient
    • Insurance Accepted Free
    • 1Accreditation(s)
  • $
    2700 East Phillips Road, Greer, SC 29650 864-235-2335
    Carolina Center for Behavioral Health offers comprehensive treatment options, including outpatient programs, intensive outpatient treatment, and hospital inpatient care. Specializing in diverse approaches like 12-step support, CBT, and motivational interviewing, the center provides tailored support for substance use recovery. Additional services include mental health support, social skills training, and case management. The facility also emphasizes transition support with ongoing recovery care and discharge planning. Comprehensive testing and assessments are available to ensure personalized treatment plans.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder Mental health treatment
    • Detox For Opioids Alcohol Benzodiazepines Cocaine Methamphetamines
    • Ages Youth (Ages 12-17)
    • Gender Female Male
    • 1Accreditation(s)
    • Medication
  • $
    634 Fairview Road, Building I, Simpsonville, SC 29680 864-228-7788
    Ascent Recovery Solutions is located in Simpsonville, South Carolina. They offer special programs for Service members, Adult men, Adult women, Court referrals, Military families, Past domestic violence, Past sexual abuse, Past trauma, Mental health disorders, HIV/AIDS, Pregnant/postpartum, Veterans, Pain management and Seniors. They provide payment assistance. They do not provide a sliding fee scale. They provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats opioid use disorder
    • Detox For Opioids
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • 3Accreditation(s)
    • Medication
  • $
    208 East 1st Avenue, Pickens, SC 29671 864-898-5800
    Behavioral Health Services of - Pickens County is located in Pickens, South Carolina. They offer special programs for Adolescents, Adult men, Adult women, Court referrals, Past domestic violence, Past sexual abuse, Past trauma, Mental health disorders, Pregnant/postpartum, Pain management and Young adults. They provide payment assistance. They provide a sliding fee scale. They provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder Mental health treatment
    • Ages Adults (Ages 26-64) Youth (Ages 12-17)
    • Gender Female Male
    • 2Accreditation(s)
    • Medication
  • $
    131 Broadbent Way, Anderson, SC 29625 864-222-9798
    Southwest Carolina Trt Ctr LLC is located in Anderson, South Carolina. They offer special programs for Adult men, Adult women, Pregnant/postpartum, Seniors and Young adults. They do not provide payment assistance. They do not provide a sliding fee scale. They provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats opioid use disorder
    • Ages Adults (Ages 26-64) Young Adults (Ages 18-25)
    • Gender Female Male
    • 3Accreditation(s)
    • Medication
  • $
    226 McGee Road, Anderson, SC 29625 864-260-4168
    Anderson/Oconee - Behavioral Health Services is located in Anderson, South Carolina. They offer special programs for Service members, Adolescents, Adult men, Adult women, Court referrals, Military families, Past domestic violence, Past sexual abuse, Past trauma, Mental health disorders, HIV/AIDS, Pregnant/postpartum, Veterans, Pain management and Young adults. They do not provide payment assistance. They do not provide a sliding fee scale. They provide medication-based treatments.
    • Available Services Transitional services Recovery support services Treats alcohol use disorder Treats opioid use disorder
    • Ages Seniors (Ages 65+) Adults (Ages 26-64)
    • Gender Female Male
    • 3Accreditation(s)
    • Medication

Counselors and therapists can help you identify factors that underly your substance use, to avoid triggers, to strengthen your motivation, and to navigate treatment options. They can also team with certified professionals to administer medication-assisted treatment. More on counseling.

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  • The state can refer you to local counseling and treatment options.
    • Services for Free Healthcare Navigator
  • Provides an interactive map for finding inpatient, outpatient, and opioid treatment facilities, as well as intervention services.

     

    • Services for Free Healthcare Navigator
  • United Way Association of South Carolina provides a comprehensive 211 service that connects individuals with local resources for substance use issues, including treatment programs, counseling, and support groups. The service is available 24/7 and offers confidential assistance to help individuals find the help they need.
    • Services for Free Healthcare Navigator
  • Mental Health America of South Carolina provides support, education, and advocacy for individuals with mental health and substance use issues. They offer resources and programs aimed at improving mental health and well-being across the state.
    • Services for Free Healthcare Navigator
  • The SAMHSA National Helpline (available 24/7 in English and Spanish) provides free, confidential information and referrals for support groups and treatment facilities to individuals facing mental and/or substance use disorders. 
    • Services for Free Mental Health Support Medication-Based Treatments
  • Confidential support through the Partnership for Drug-Free Kids Hotline helps families make a plan of action to address a child’s substance use. It is available in English and Spanish. 
    • Services for Free
  • The AAAP Member Addiction Psychiatrists is a directory of addiction psychiatrists and relevant health professionals trained to provide treatment for addiction and co-occurring mental illnesses. 
    • Services for Mental Health Support Medication-Based Treatments
  • American Psychological Association member psychologists.
    • Services for Free Healthcare Navigator Mental Health Support

Support groups provide a space for getting social support, a sense of empowerment, and motivation from people who have faced — or are facing — similar challenges and circumstances. More on support groups.

Showing 1-5 out of 5 results

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  • Get involved with local non-profits working to change perceptions, policies, and laws to improve the lives of those in the recovery community. Many of these organizations also provide peer recovery support services.

     

  • Narcotics Anonymous (NA) is a Fellowship for anyone seeking to stop using drugs, including alcohol. NA uses a twelve-step approach focused on spiritual and personal growth steps for lasting sobriety. 
    • Services for Free
  • Alcoholics Anonymous (A.A.) is a Fellowship aimed at helping alcoholics achieve sobriety through the twelve-step approach to recovery. Shared experiences and a structured, spiritual approach are central to A.A. 
    • Services for Free
  • SMART Recovery is a secular recovery community that uses mutual support and focuses on self-empowerment to help participants gain independence from triggering behaviors.  
    • Services for Free
  • The Oxford House is a shared drug and alcohol-free residence for those in recovery from substance use disorder. 

How to Choose Treatment in Greenville

If you’re trying to find the best care for your needs in Greenville, you’ll find detox, residential, outpatient, long-term recovery housing, and medications for addiction treatment (MAT). Pregnant people and those who use substances intravenously receive priority admission to detox centers. While detox — including 24/7 detox — is available, beds may fill up quickly. If this happens and you need immediate care, you can call programs for a referral and ask for bridge care while you wait. If you are on South Carolina Medicaid, you should be eligible for rehab coverage. Most private insurance plans are accepted, and if you don’t have insurance, there are free or very low-cost programs available. Some providers may be able to arrange payment assistance. If you are looking for specialized or luxury residential programs — or residential care for adolescent girls — you’ll likely need to look beyond Greenville. 

Can I start detox in Greenville today?

Yes — help can start today. Call a clinic or local hospital to begin medication for withdrawal and stabilization. Call first to confirm space. 

When you call, ask about language services and Greenlink Transit access as needed. If they’re full, ask for bridge care (telehealth, interim medications, groups) so you can start right away.

Do I need to travel for rehab, or is care available in Greenville?

You usually don’t have to travel. Greenville offers detox, inpatient, outpatient, MAT, telehealth, and sober living. If you are looking for residential care for teenage girls, LGBTQIA+-dedicated programs, or luxury amenities, you may need to travel. You may also need to look outside of Greenville if detox beds and recovery houses in the area are full. 

Paying for Addiction Treatment in Greenville

How much does rehab cost in Greenville?

Rehab prices can look overwhelming, but most people pay far less once insurance or financial aid is applied. Before you start treatment, ask for a written estimate, whether the program is in-network for your plan (and if prior authorization is required), and ask about sliding-scale fees or financial help. Learn more about the cost of rehab

Typical Costs (publicly funded or community-based programs; not luxury):

  • A little over three months of residential care in Greenville usually costs about $21,130 if you pay out of pocket. With insurance that covers 80%, you’d pay closer to $4,230 total — or about $1,300 per month.

  • A three-month intensive outpatient program in Greenville usually costs about $9,150 if you pay out of pocket. With insurance that covers 80%, you’d pay closer to $1,830 total — or about $610 per month.

  • A four-to five-month non-methadone outpatient program in Greenville usually costs about $5,190 if you pay out of pocket. With insurance that covers 80%, you’d pay closer to $1,040 total — or about $230 per month.

  • About two years of methadone maintenance in Greenville usually costs about $18,650 if you pay out of pocket. With insurance that covers 80%, you’d pay closer to $3,730 total — or about $170 per month.

What private insurers provide in-network coverage in Greenville?

Many major plans include in-network options — commonly Blue Cross Blue Shield of South Carolina, Aetna, Cigna, UnitedHealthcare, Humana, and others. Always confirm network status, prior authorization, and your out-of-pocket costs with your plan and the facility.  

Are there free rehab programs in Greenville?

Yes — you can find free or low-cost programs in Greenville. If you don’t have insurance or resources, you can still get care through government-funded providers and nonprofit organizations. Start by dialing 2-1-1 for referrals, calling the Phoenix Center (Greenville County’s public substance use authority), or using the Free, Sliding Scale Fee, and Payment Assistance filter options on this directory to find no-cost and low-cost options. If you do have insurance, your plan may cover some or even the full cost of treatment — you’ll need to call the facility to confirm.

  • South Carolina 2-1-1: Dial 2-1-1 for referrals to low- or no-cost treatment, transportation, shelters, and other supports. 

  • Phoenix Center: Serving Greenville County, this center can connect you to sliding-fee and no-cost treatment options, as well as state block-grant funding through the South Carolina Department of Behavioral Health and Developmental Disabilities (DAODAS).

  • Faith-based programs: Miracle Hill Ministries’ Overcomers, Renewal, and Adult & Teen Challenge of South Carolina provide long-term, low-or-no-cost residential care. 

  • Salvation Army: Call for help with referrals to nearby adult rehabilitation centers. 

  • Emergency stabilization: In a crisis, (such as life-threatening withdrawal or intoxication), call 911 or S.C. Mobile Crisis at 1-833-364-2274 (or dial 988). Hospital emergency departments, such as Prisma Health Greenville Memorial, will stabilize you regardless of ability to pay. You may receive a bill later for hospital or transport services; financial-assistance programs are available through local hospitals.

Keep in mind there are many free non-clinical peer support and counseling resources available as well.

Best Rehabs in Greenville

What does “best” mean?

“Best” means best-for-you — care that matches your level of need, works with your insurance and budget, and fits your life (location, schedule, family). Start by listing what you need and what your plan covers, then choose an option you can start now and stick with. The programs below are examples of options that may be a good fit depending on your needs — explore them to see which might be right for you.

Facilities are included based on licensing, accreditations (when noted), years in operation, and endorsements from trusted local organizations. Always verify current availability and coverage. This is not a definitive ranking.

What are the best rehabs in Greenville?

Strong local standouts include Phoenix Center (provides a full continuum of substance use care) and The Carolina Center for Behavioral Health (a Joint-Commission-accredited hospital offering detox, inpatient care, and treatment for co-occurring mental health). You can find several other established providers with residential, outpatient, and crisis/detox access in Greenville. Before you choose, call to make sure there are current openings, the level of care offered, and in-network coverage for your insurance plan. Ask for a written estimate and bridge care if beds are full.

What are the best rehabs for women in Greenville? 

One good option is Phoenix Center’s Serenity Place, a residential program that allows moms and preschool-aged children to live together during care and provides prenatal services for pregnant women. Another option is Miracle Hill’s Renewal Center, which offers a women’s Christian residential program at low cost. When you call, check available care levels and, if needed, whether they offer childcare and transportation support.

What are the best rehabs for teens in Greenville?

Consider Phoenix Center (operates an accredited, county-endorsed residential program for teenage boys ages 13–17) and The Carolina Center for Behavioral Health (admits adolescents ages 12–17 for short-term stabilization). If you are looking for a teenage girls’ residential program, you may need to search outside of Greenville. The best option will depend on your needs, such as whether or not you want to continue school and the level of family involvement. 

What are the best Christian rehabs in Greenville?

Two noteworthy Christian residential programs are Miracle Hill Ministries’ Overcomers for men and Renewal for women. Both are donation-funded and low-cost. Celebrate Recovery offers groups and church-hosted meetings. You can also call other providers and ask if they have a spiritual recovery track available. If you are looking for non-Christian faith-based programs, you may need to look outside of Greenville.    

What are the best rehabs for co-occurring mental health in Greenville?

Strong options include The Carolina Center for Behavioral Health (offers a program for people with substance use and co-occurring mental health conditions, including psychiatric care and therapy), Phoenix Center (provides evidence-based outpatient care for co-occurring mental health needs and can coordinate with psychiatrists as needed), and Prisma Health Marshall I. Pickens (psychiatric hospital-based care for mental health needs and substance use with a dedicated inpatient depression program). When you call, specify your co-occurring mental health needs to make sure you find the best program for you.  

What are the best detox centers in Greenville?

Check out Phoenix Center - Gibson Detoxification Unit (24/7 inpatient detox for multiple substances with MAT), Prisma Health Marshall I. Pickens (hospital-based detox for those with serious medical and psychiatric needs), and Recovery Centers of America at Greenville - Detox Unit (private facility with medical detox and MAT). You can call and ask if beds are available, what the detox process looks like, and what substances are treated. 

What are the best intensive outpatient (IOP) programs in Greenville?

Stand out options include The Carolina Center for Behavioral Health (hospital-based IOP for substance use and mental health with medication management), Phoenix Center ( state-approved evening IOP program), and Prisma Health Marshall I. Pickens (IOP program with care for substance use and mental health). Call to ask about scheduling options (days, evenings, etc.), how often groups meet, whether telehealth is provided, and MAT policy as needed.

Choosing the Right Rehab

How do I choose the right level of care?

Start with an independent assessment from a clinician who specializes in substance use problems and isn’t employed by a treatment center. They can help you choose between treatment options like outpatient, residential, hospital inpatient, withdrawal management (detox), and medications used alongside therapy. Learn more about choosing the right rehab for your needs

Who can help me choose the best rehab in Greenville right now?

Call the SC HOPES line (1-844-724-6737) for 24/7 clinical support and navigation. You can also contact Phoenix Center intake (864-467-3790) for assessments and local referrals. FAVOR Upstate can help you with free peer navigation and coaching. When you call, say: “I’m in Greenville and need [detox/IOP/residential]; I have [South Carolina Medicaid/private insurance/other]. Do you have openings this week?”

How can I check if a Greenville rehab is licensed (and accredited)?

Before you choose, look up whether a facility is licensed by the South Carolina Department of Public Health (DPH). If you’re unsure, call and ask the facility for its license number or call DAODAS to verify. You can also ask about national accreditation (The Joint Commission or CARF). Accreditation isn’t required, but it’s a useful extra quality signal. Learn more about accreditation and other indicators of quality care

Compare accredited rehab centers in Greenville. Browse a wide range of drug and alcohol treatment options, including inpatient centers, outpatient centers, detox centers, methadone clinics, support groups, and counseling options.

StartYourRecovery.org provides facility information using publicly available data from the Substance Abuse and Mental Health Services Administration as well as other sources. We cannot independently verify the accuracy of all data. StartYourRecovery.org does not guarantee the quality of care or results of working with any provider or treatment facility. Please contact us if you are the proprietor of a facility and have updates or corrections to site content.

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